Effects of Shear Wave Velocity Profile of Soil on Seismic Response of High Rise Buildings

There is, nowadays, a conspicuous demand for the high rise buildings in the high-density dwellings of the urban areas; in consequence, harnessing the whiz-bang numerical simulations plus conducting the rigorous experimental studies so as to design and construct such prodigious structures would be essential. Thus, the appropriate parameters for modeling the structure and the soil medium in the Soil-Structure Interaction (SSI) system should be selected. The soil-structure interaction is referred to the process in which the soil response is told on by the structure motion whilst the latter is affected by the soil motion. The current research zeroed in on the soil shear wave velocity and its influence on the superstructure performance. Invoking the weighted average shear wave velocity with the aim of calculating the soil shear modulus, which is closely related to the strength and deformation characteristics of the soil, has been a hotly debated issue since the aforesaid parameter was posited by a plethora of codes and regulations to obtain the soil site classification required for the earthquake design. To that end, the numerical model, having two assorted profiles associated with the shear wave velocity, namely, the in situ non-uniform profile (Case A) and the equivalent uniform profile (Case B), was built by means of FLAC3D, capable of analyzing the complex interaction issues via the direct method whereby the entire system of the structure-foundation-soil is modeled and analyzed in one single step. To put it in a nutshell, employing the weighted average shear wave velocity for the entire soil mass in parsing of the 3D seismic soil-structure interaction problems would be accused for ending up with somewhat unreliable results, e.g., underestimated drift ratio and building deformation, which might be the culprit of the damage to the building and possibly the death of the residents residing in the earthquake-prone zones

Transcriptional interference by RNA polymerase III affects expression of the Polr3e gene.

Overlapping gene arrangements can potentially contribute to gene expression regulation. A mammalian interspersed repeat (MIR) nested in antisense orientation within the first intron of the Polr3e gene, encoding an RNA polymerase III (Pol III) subunit, is conserved in mammals and highly occupied by Pol III. Using a fluorescence assay, CRISPR/Cas9-mediated deletion of the MIR in mouse embryonic stem cells, and chromatin immunoprecipitation assays, we show that the MIR affects Polr3e expression through transcriptional interference. Our study reveals a mechanism by which a Pol II gene can be regulated at the transcription elongation level by transcription of an embedded antisense Pol III gene

Definition of Spam 2.0: New Spamming Boom

The most widely recognized form of spam is e-mail spam, however the term “spam” is used to describe similarabuses in other media and mediums. Spam 2.0 (or Web 2.0 Spam) is refereed to as spam content that is hosted on online Web 2.0 applications. In this paper: we provide a definition of Spam 2.0, identify and explain different entities within Spam 2.0, discuss new difficulties associated with Spam 2.0, outline its significance, and list possible countermeasure. The aim of this paper is to provide the reader with a complete understanding of this new form of spamming

Prevalence of Hepatitis B virus, Hepatitis C virus and human immunodeficiency virus infections among patients candidate for orthopedic trauma surgeries

Background: Infectious diseases are major public health problems, among which blood-borne ones are the most important infections. Patients who undergo orthopedic surgery are at higher risk of transmitting infectious diseases from and to others, due to repeated blood examinations and injection, drains secretion and receiving blood products. Accordingly, in this study we determined prevalence of Hepatitis B Virus (HBV) Hepatitis C Virus (HCV) and human immunodeficiency Virus (HIV) infections in patients who underwent surgery in a general training hospital. Methods: In this cross-sectional study the prevalence of HBV, HCV, and HIV infections was determined among 320 patients under orthopedic trauma surgeries in a general training hospital in Tehran, Iran from 2009 to 2011. Associations of these rates with age, gender, marital status, residence location, substance abuse history, hospital admission history, previous surgery, blood transfusion, dentistry procedures, and previous medical history were also assessed. Results: A total of 320 patients (290 male, 30 female) were studied. Ten patients (3.2) had at least one of these three infections. Totally 10 patients (3.2), 2 subjects (0.6), and 8 patients (2.5) had HCV, HIV, and HBV infections, respectively. None of the evaluated variables had significant relationship with HCV, HBV, and HIV infections (p > 0.05). Conclusion: According to the obtained results, routine use of diagnostic tests for infectious disease such as HIV and viral hepatitis is recommended and should be considered before orthopedic operations

Risk of superior gluteal nerve injury after using ante-grade femoral nailing

Antegrade intramedullary femoral nailing (AIFN) is used as the preferred treatment for diaphyseal and subtrochanteric femur fractures. Nevertheless, clinically important complications associated with obtaining nail entry including loss of hip abductor strength, chronic hip pain, heterotopic ossification and femoral head osteonecrosis have been previously shown.This study was aimed to evaluate the risk of injury to the superior gluteal nerve when Ante-grade femoral nailing is used for insertion. In current study, 25 patients with femoral shaft fractures were included in this study that 21 were male with an average age of 25.40 years, Also 4 cases were female with an average age of 28.20 years. The patients were between the ages of 93 to 05 years. EMG-MCV was taken from all patients and were reported by neurologist. Plain radiographs were taken from all patients. Pain intensity of patients in the last month were identified from 4 to 944 according to the patients statements. The frequency of patients with subjective lameness separately with or no signs was determined. In terms of the pain score, its average among all patients was calculated to be 4.92, while the average of 4.75 among men was calculated. Among women, the average was 5.60. All patients had a mean duration of 3.64 months for using crutches, that the average duration of 3.80 months for men and 3 months for women were calculated.In terms of subjective limping, 15 patients (60) complained from limping, while 10 people were not affected (40 ), of which, 12 patients (80) was belonged to men group and 3 patients (20) were assigned in women group. 5 patients were diagnosed with atrophy of gluteus medius and gluteus minimus muscles that, 3 patients were male (60) and 2 cases (40) were women respectively. EMG-NCV indicated that the Superior gluteal nerve injury had occurred in 2 patients (8) and myogenic damage of gluteus medius and gluteus minimus muscles in 5 patients (20). Our study indicated that the superior gluteal nerve injury had occurred in 2 8 of patients and myogenic damage of gluteus medius and gluteus minimus muscles in 20

Marshall syndrome in children referred to specialist clinic of Imam Khomeini Hospital of Ilam, Iran, 2012

Periodic fever syndrome is a self-inflammatory disease. Since the disease is benign and self-limiting, the present study aimed to achieve a model to detect and differentiate it from other infectious diseases .In this study all children residing in Ilam who were suspected of Marshall Syndrome were examined. We chose a sample comprising children referred to Imam Hospital clinic of Ilam in 2012. Inclusion criteria consisted of more than three periods of fever without a source of infection, fever periods shorter than 5 days and repeated at intervals of about one month. The collected data were analyzed using SPSS software 16. We used both of descriptive and inferential statistics, Kolmogrov smirnov, Chi-square. Significance level of P ≤ 0.05 was considered. The average of patients' age was 4.9 ± 1.8 months and their gender perception was 85.7 male and 14.3 female. In this study the average age of symptoms emergence was 48.33 ± 23.25 month. The average of fever periods in surveyed patients was 4.09 ± 0.88 days (minimum 3 days & maximum 5 days) and the intervals between fever periods was 40.23 ± 16.84 in average. The applied treatments in this study were Prednisolone and Ttonsillectomy. There was significant relationship between age and the symptoms (P<0.007). By having a true perception of Marshall Syndrome using diagnosis criteria, we could prevent uncontrolled prescription of antibiotics and their possible side effects, and it is a positive step towards reducing healthcare costs

Effects of light regimes on growth and survival of Penaeus semisuleatus

We investigated the possible effects of light regimes on growth and survival rate of juvenile shrimp Penaeus semisuicants cultured in Bushehr Province, southern Iran. Five light regimes each with three replications were applied for 30 days. The treatments were 24 1 0, 18 / 6, 12 1 12, 6 1 18 and 0 124 hours of light and darkness. We found that the treatment 12 7 12 hours of light and darkness was better than 18 1 6 and significantly superior to other treatments (P<0.05). The lowest growth rate was seen in the treatment 24 / 0 (P<0.001 ). We did not find a significant difference in the survival rate of the shrimps cultured in the light and darkness treatments (P<0.05)

Software-defined networking for ubiquitous healthcare service delivery

The growth of the mobile, portable devices and the server-to-server communication through cloud computing increase the network traffic. The dependence of the ubiquitous healthcare service delivery on the network connectivity creates failures that may interrupt or delay the treatment plan with adverse effects in patients’ quality of life even leading to mortality. In the present work, we propose the incorporation of Software Defined Networking (SDN) features in the healthcare domain in order to provide the appropriate bandwidth and guarantee the accurate real time medical data transmission independently of the connectivity of the ISP provider. The SDN controller monitors the network traffic and specifies how traffic should be routed providing load balancing, lower delays and better performance. Finally, the proposed healthcare architecture addresses the SDN scalability challenge by incorporating the logically centralized control plane using multiple distributed controllers. A 2-tier hierarchical overlay is formed among SDN controllers following the principles of peer-to-peer networking

Molecular identification of bacterial and fungal pathogens in certain disease-free shrimp

At present, the aquaculture industry to provide proper instructions in the field of health management, including production of Specific Pathogen Free shrimp (SPF), require sensitive and reliable methods for the detection and identification of pathogenic microorganisms. Molecular methods which used in the detection of microorganisms have a high discriminatory power in the taxonomy and in relation to libraries in the world. On the other hand, the accurate identification of microorganisms, providing the genetic data bank of shrimp pathogens and maintenance of these strains is the step to promote further research on the mechanisms of pathogenesis of pathogens, diagnosis, treatment, prevention of disease, identify indigenous production kits, diagnosis re emerging and emerging diseases and their origin. Therefore, in this project, by using ribotyping technique, native isolated pathogenic bacteria and fungi were identified and recorded in the gene bank database center. During sampling of shrimp and water of Specific Pathogen Free shrimp center, 40 bacterial strains were isolated, which 8 of them had the most frequency and identification based on 16S rDNA sequencing was performed. Bacteria identified are: Vibrio nigripulchritudo strain IS013(GenBank:KP843725), Vibrio brasiliensis strain IS014 (GenBank:KR186076), Vibrio rotiferianus strain IS015 (GenBank:KR186077), Vibrio azureus strain IS012 (GenBank:KJ018724.1), Vibrio owensii strain IS016 (GenBank:KR186078), Agarivorans gilvus strain IS017 (GenBank:KR186079), Vibrio brasiliensis IS018 (GenBank:KR186080) and Vibrio alginolyticus strain IS019 (GenBank:1817854), which were recorded in The World Bank genes. In this study fungal isolates were not detected

The impact of depression, personality, and mental health on outcomes of total knee arthroplasty

Background: Precise assessment of preoperative mental health and psychological determinants may be useful in identifying patients at risk for poor postoperative outcomes of total knee arthroplasty (TKA). The aim of this study was to investigate the influence of psychological status and physical and mental health on the outcome of patients undergoing TKA. Methods: Fifty-two patients undergoing unilateral TKA were assessed preoperatively with Oxford Happiness Inventory, Eysenck Personality Inventory, 12-item short form health survey (SF-12), and Knee Injury and Osteoarthritis Outcome Score (KOOS) for evaluating depression, personality traits, physical and mental health, and function, respectively. At 1 year after surgery, health-related quality of life (HRQL) and function were assessed using the SF-12 and KOOS. Results: HRQL and function of all personality traits increased significantly after TKA, without significant difference among them. Extroversion and neuroticism did not have significant correlation with subjective well-being, HRQL, and function before and after surgery. Subjective well-being and the baseline physical and mental health scores were correlated strongly and directly with postoperative physical component summary, mental component summary, and KOOS scores and their improvement. Among many factors that significantly affected the outcomes of TKA, the only independent predictor of physical, mental, and functional outcome was depression. Conclusions: Outcomes of surgery were not significantly different among diverse personality traits. Patients with less depressive symptoms and higher baseline mental and physical scores had significantly greater improvement in HRQL after surgery. The only independent factor affecting the physical, mental, and functional outcome was depression. © 2020 by The Korean Orthopaedic Association